Giridharan Periyasamy, Ph.D.
Genome Institute of Singapore
Singapore
Singapore
Dr.
Periyasamy is a platform head at the Centre for High Throughput
Phenomics (CHiP-GIS) at the Genome Institute of Singapore. His research
focuses on the cancer biology, drug resistance, and signaling pathway
networks of human diseases as well as on ways to model these disorders.
His current specific interest is the elucidation of novel mechanisms of
drug resistance through the discovery/identification of novel gene
function(s) and phenotypes using RNAi-mediated gene silencing or cDNA
overexpression. He is also developing a robust and comprehensive panel
of 3-D cell culture models from patient-derived primary cells that can
be used to characterize different disease phenotypes and investigate the
chemo-response of cells to novel or known drugs. The hope is that this
work can lead to the establishment of an array of next generation
preclinical 3-D tissue models for predictive toxicology screening and
validation. Prior to his current position, Dr. Periyasamy worked as a
scientific director of the HTS/HCS Screening Core Facility at the
National Centre for Biological Sciences in India and was a group leader
at Piramal Life Sciences in Mumbai, India. He studied at the Centre for
Biotechnology at Anna University in Chennai, India, where he obtained
his Ph.D. in biotechnology.
